How the humble Gin & Tonic may save the world from COVID 19.

Note this is not medical advice. Never take any medication or assume you know the side effects or benefits of anything to treat COVID 19 or any other malady. Always take direction from your doctor. Now sit back, relax and have a Gin and Tonic. After all, what else do you have to do in lockdown?

EDIT: Alberta HOPE Trial.
The Alberta HOPE TRIAL for HCQ Cancelled in Fraudulent terms. WHY?

References

Complete research here: The Best Laid Plans COVID-19

There is a lot of negativity around the discussion about Hydroxychloroquine and Azithromycin. As a result, people are saying they wouldn't take this particular drug until there are 'official' studies completed. These could take years.

Note that there have been a number of press articles and 'studies' recently circulated that suggest Hydroxychloroquine is both deadly and does not work. Yet it is still safe to use for Lupus, Malaria and Rheumatoid Arthritis! Please do your research, these are false and dangerous narratives. More and more doctors worldwide have been successfully treating patients with this drug (as they did with previous coronavirus outbreaks). If you require any specific assistance finding more information, please don't hesitate to message the author.

However, hydroxychloroquine is the safer version of chloroquine, a synthetic version of quinine, the active ingredient in tonic water. https://blogs.sciencemag.org/pipeline/archives/2020/03/20/chloroquine-past-and-present

Tonic Water?

Tonic Water was invented to make it easier to take quinine to protect as a prophylactic against malaria. Its common use dates back to the 1800's. It was first commercially produced in 1858.

Yes, that bitter tasting fizzy drink which became a staple around the world to the point of being a legend! The British, (being what we are!) decided it needed a bit of a kick to wash it down. And thus was born the infamous Gin and Tonic.

"It is a curious fact, and one to which no-one knows quite how much importance to attach, that something like 85 percent of all known worlds in the Galaxy, be they primitive or highly advanced, have invented a drink called jynnan tonyx, or gee-N'N-T'N-ix, or jinond-o-nicks, or any one of a thousand variations on this phonetic theme.

The drinks themselves are not the same, and vary between the Sivolvian 'chinanto/mnigs' which is ordinary water served just above room temperature, and the Gagrakackan 'tzjin-anthony-ks' which kills cows at a hundred paces; and in fact the only one common factor between all of them, beyond the fact that their names sound the same, is that they were all invented and named before the worlds concerned made contact with any other worlds."

Douglas Noel Adams (DNA), The Restaurant at the End of the Universe

We might have discovered just how much importance to attach to these prophetic words written in jest.

The history of tonic water and quinine is easy to find. It has been around almost forever. Please note that the current commercial versions of tonic water contain very little quinine. Quinine is toxic if improperly taken, (as are many drugs). Do not try and self-medicate without the advice of your doctor.

So, for Hydroxychloroquine we are now talking about an 'off label' use of a medication that has been safely used on millions, if not billions, of people since the 1800's (or earlier in various forms).

Hydroxychloroquine is not just a malaria prophylaxis; it is an autoimmune therapy also. However, its use goes beyond both, over its long history and lineage. This is just a simple overview of why it works.

HCQ lowers blood sugar. This decreases the probability of the infection triggering a cytokine storm, leading to multiple organ failure. This cytokine storm is a primary killer in most Influenza Like Illnesses (ILI).
HCQ prevents viral uptake by cells thus making it a highly effective prophylaxis.
HCQ increases the rate of viral shedding thus reducing the length of time and severity of any viral infection.
HCQ is effectively used to safely treat autoimmune diseases such as Lupus and Rheumatoid Arthritis. It is an immune suppressant that prevents any ILI virus from triggering a cytokine storm.

An alternate to HCQ with similar properties (and possibly more significant benefits) is Artemisia Annua (Sweet Wormwood or Sweet Annie - See Below). The Chinese made Tea while the British poured a G & T.

[EDIT]
You know how many other medications are commonly used 'off label' i.e. not for the use on the label? Almost all of them!

If you went to Africa (back when travel was allowed), your doctor probably gave you this drug to protect you from malaria. People take this without a thought for weeks or more. Lupus patients take this as a matter of course, without a thought, for years. Those with rheumatoid arthritis also take this medication with great success. Note that long term use has some side effects. These drugs should never be taken without the advice and/or supervision of a doctor.

If you were given Hydroxychloroquine for COVID 19 for around 6 days, it would most likely be life saving. It has in almost all of the thousands of people tested in small trials throughout the world. It was used to treat Avian Flu (1997), SARS (2003), MERS (2015) and many other diseases that cause a cytokine storm (such as lupus) for decades. So, why is it now so bad and risky?

Some, patients will sadly still die after contracting COVID 19 despite taking this medication or indeed any other treatment. Those sad cases are a tiny proportion of those treated. However, every reported case I have researched, the underlying complications and/or delayed treatment has been found to be the primary factor though. This is all anecdotal evidence until you take the dozens of studies and add them together. As such, we already have had large scale randomized testing of this drug, provided under doctors supervision, in combination with Azithromycin.

So, right now these are the few choices for patients dying with COVID 19 complications.

Dying on a ventilator. [Link] & [Link (check links in article)]
Taking an expensive and risky experimental drug on trial for Ebola (Remdesivir).
Having a risky blood (plasma) transfusion from a previously infected patient.
Taking an 'off label' medication that has already successfully treated thousands.

https://www.cdc.gov/coronavirus/2019-ncov/hcp/therapeutic-options.html

Some positive results are being reported for Remdesivir (a minimal 4% benefit in mortality reduction in current trials) and plasma transfusion, but neither of those have gone through rigorous double-blind studies in the treatment of COVID 19 either. So, why are these treatments acceptable and Hydroxychloroquine is not?

The CDC is not expected to publish results of Hydroxychloroquine trials before mid 2021. Would you really wait for double-blind studies to come back if your very life depended on it?

As of April 29th, 2020, the current CMAJ treatment guidelines remove almost all reasonable medication treatment protocols without any evidence to support the decision.

https://www.cmaj.ca/content/early/2020/04/29/cmaj.200648

“Because the likelihood of death from COVID-19 in patients with nonsevere disease is extremely low (in the range of 1/1000), we are very confident that antiviral drugs will have little or no effect on mortality in such patients.” (Ye, 2020)

This article states that not using proven, cheap and safe treatments for COVID 19 is justifiable because it is no more dangerous than flu with a mortality rate of 0.1%. However, the CMAJ guidelines support lockdowns and known high risk protocols for COVID 19. These guidelines suggest corticosteroids for COVID 19. This makes no sense at all.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30628-0/fulltext

“As during previous pandemics (severe acute respiratory syndrome and Middle East respiratory syndrome), corticosteroids are not routinely recommended and might exacerbate COVID-19-associated lung injury.” (Mehta, 2020)

https://pubmed.ncbi.nlm.nih.gov/30917856/

"In patients with influenza pneumonia, corticosteroid use is associated with higher mortality."

A vaccine, the only other long term option presented, could be 12 to 18 months away (if at all**). Also, we have a vaccine for H1N1 (also known as Spanish Flu, Swine Flu and since 2009, seasonal flu). H1N1 still kills tens of thousands or more every year. So, even with a vaccine, a treatment is also required to save lives.

For those who need hospitalization and end up on a ventilator, COVID 19 has proven fatal, if not treated early and appropriately, in almost every case.

There are two primary causes of death being reported in relation to COVID 19. The cytokine storm (similar to an autoimmune reaction such as in Lupus) and pneumonia. So, ask yourself, why Hydroxychloroquine with Azithromycin (a common antibiotic used for chest infections) works?

Associated with the cytokine storm, a significant factor in this co-morbidities for COVID 19 is high blood sugar. This has long been known to be directly related to cytokine storm deaths in influenza and other coronavirus infections [Link]. This is also the primary final stage for COVID 19 patients who are not treated early enough.

This may explain why Hydroxychloroquine is so effective in early treatment of COVID 19. Not only is it an autoimmune drug (for Lupus and Rheumatoid Arthritis) that suppresses a cytokine storm, it also helps lower blood sugar levels. [Link] [Link]

Can you really afford to wait? I couldn’t and wouldn't. I haven't had a drink in almost four decades. But bottoms up! Pour me a G & T (derivative)!

Now back to your regularly scheduled 'programming' update. Welcome to Stepford, 1984 style. How a to program a population to accept the 'new normal'. Remember to eat your Soylent Greens.

References

**The common cold is a coronavirus (OC43). Coronaviruses account for 10%-30% of respiratory infections worldwide (as per Dr. Fauci) but have never locked down the world. https://www.cdc.gov/coronavirus/types.html

There has never been a vaccine created for any human coronavirus; https://www.cdc.gov/coronavirus/general-information.html

Less than 2,000 'cases' (not 'deaths') in China alone, & drug makers 'rushed' to create a vaccine. This, despite no-one ever developing such a vaccine before. A cure for the common cold - Woo Hoo (or is that Wuhan). 50 years trying with no success for any coronavirus!

Jan 23 2020. https://www.wsj.com/articles/drugmakers-rush-to-develop-vaccines-against-china-virus-11579813026

Canada clamoring to cure the new ‘common cold’. https://globalnews.ca/news/6466954/coronavirus-outbreak-vaccine-research/

Thanks Dr. Fauci for suddenly jumping on the vaccine money train. Maybe you will cure the common cold as well!!! https://jamanetwork.com/journals/jama/fullarticle/2759815

We should stop comparing COVID 19 to the flu as H1N1 etc. have a vaccine.

COVID 19 - the new & improved 'Common Cold'. What is this really all about?**

For clinical trials see:

https://www.nih.gov/news-events/news-releases/nih-clinical-trial-hydroxychloroquine-potential-therapy-covid-19-begins

Hydroxychloroquine (the safer successor to Chloroquine and Quinine)

A 100% reduction in mortality for a $20 treatment.

https://www.mediterranee-infection.com/early-treatment-of-1061-covid-19-patients-with-hydroxychloroquine-and-azithromycin-marseille-france/

https://www.mediterranee-infection.com/wp-content/uploads/2020/04/azithroquine_manuscript-soumis.pdf

https://www.mediterranee-infection.com/early-treatment-of-1061-covid-19-patients-with-hydroxychloroquine-and-azithromycin-marseille-france/

https://theconversation.com/blood-sugar-levels-may-influence-vulnerability-to-coronavirus-and-controlling-them-through-conventional-means-might-be-protective-136592

http://www.advbiores.net/article.asp?issn=2277-9175;year=2016;volume=5;issue=1;spage=145;epage=145;aulast=Sheikhbahaie

https://www.scientificamerican.com/article/how-blood-sugar-can-trigger-a-deadly-immune-response-in-the-flu-and-possibly-covid-191/